SCHEMBL26739953

SCHEMBL26739953

CCOC1C(n2cnc3c(N)ncnc32)O[C@](C)(CO)C1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.55
▸ PI4KA P42356 2/20 0.53
▸ PI4K2B Q8TCG2 2/20 0.53
▸ PI4K2A Q9BTU6 2/20 0.53
▸ PI4KB Q9UBF8 2/20 0.53
▸ HSP90B1 P14625 1/20 0.51
▸ ADORA3 P0DMS8 5/20 0.50
▸ ADORA2A P29274 4/20 0.50
▸ ADORA1 P30542 2/20 0.50
▸ AHCY P23526 2/20 0.50
▸ PRMT5 O14744 1/20 0.50
▸ WDR77 Q9BQA1 1/20 0.50
▸ DPP4 P27487 1/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ SLC28A1 O00337 1/20 0.50
▸ MAP3K7 O43318 1/20 0.50
▸ SLC28A2 O43868 1/20 0.50
▸ GAPDH P04406 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ ADORA2B P29275 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14946260 0.85 PRMT5 (0.65) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL2318607 0.85 PRMT5 (0.65) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL29815824 0.85 PRMT5 (0.65) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL6426564 0.85 PRMT5 (0.65) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL3436912 0.85 PRMT5 (0.65) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL14853754 0.85 PRMT5 (0.65) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL12170639 0.84 PI4KA (0.57) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL16184127 0.83 GAA (0.50) GAAPI4KAPI4K2BPI4K2API4KB
SCHEMBL749584 0.83 PI4KA (0.56) PI4KAPI4K2BPI4K2API4KBADORA3
SCHEMBL749583 0.83 PI4KA (0.56) PI4KAPI4K2BPI4K2API4KBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348522-A1 METHOD FOR PRODUCING BICYCLIC PHOSPHORAMIDITE PFAS, ENPP1, NAAA GAA 1193/4885PI4KA 933/4885PI4K2B 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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