Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11508254 | 0.84 | TSHR (0.40) | ALDH1A1TDP1MAPTL3MBTL1MEN1 | |
| SCHEMBL11510417 | 0.78 | TDP1 (0.53) | ALDH1A1TDP1MAPTL3MBTL1MEN1 | |
| SCHEMBL11518522 | 0.77 | TACR1 (0.33) | MAPTLMNAGAA | |
| SCHEMBL384635 | 0.73 | CYP1A2 (0.50) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL11519375 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11520202 | 0.71 | MAPT (0.48) | ALDH1A1TDP1MAPTL3MBTL1MEN1 | |
| SCHEMBL10256336 | 0.69 | CYP1A2 (0.52) | ALDH1A1FBP1TDP1MAPTL3MBTL1 | |
| SCHEMBL11516735 | 0.69 | TSHR (0.44) | ALDH1A1TDP1MAPTL3MBTL1MEN1 | |
| SCHEMBL11519652 | 0.69 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPTLMNAGAA | |
| SCHEMBL4622230 | 0.69 | CRHBP (0.41) | ALDH1A1TDP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171446-A | Indazole compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1979-10-16 | — | — | US | disclosed |