Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510417 | 0.78 | TDP1 (0.53) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL11516735 | 0.73 | TSHR (0.44) | ALDH1A1TDP1TSHRHSD17B10CYP2D6 | |
| SCHEMBL7793971 | 0.73 | DCTPP1 (0.44) | ALDH1A1TDP1TSHRDCTPP1KDM4E | |
| SCHEMBL11518804 | 0.73 | ESR1 (0.41) | ALDH1A1TSHRCYP3A4ESR1CYP2D6 | |
| SCHEMBL2777976 | 0.73 | TSHR (0.45) | ALDH1A1TDP1TSHRHSD17B10CYP1A2 | |
| SCHEMBL11508254 | 0.72 | TSHR (0.40) | ALDH1A1TDP1TSHRCYP3A4KDM4E | |
| SCHEMBL384635 | 0.71 | CYP1A2 (0.50) | ALDH1A1TDP1TSHRHSD17B10CYP1A2 | |
| SCHEMBL3192684 | 0.69 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL11520195 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TDP1HSD17B10MAPTGAA | |
| SCHEMBL11518265 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171446-A | Indazole compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1979-10-16 | — | — | US | disclosed |