Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793971 | 0.79 | DCTPP1 (0.44) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL11510417 | 0.78 | TDP1 (0.53) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL11519652 | 0.73 | ALDH1A1 (0.43) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL11521224 | 0.73 | ESR1 (0.37) | TSHRTDP1MAPTCYP2D6CYP2C9 | |
| SCHEMBL11508254 | 0.72 | TSHR (0.40) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL384635 | 0.71 | CYP1A2 (0.50) | TSHRTDP1HSD17B10ALDH1A1MEN1 | |
| SCHEMBL10797324 | 0.71 | TSHR (0.46) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL6642803 | 0.70 | TSHR (0.37) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL26507120 | 0.69 | TSHR (0.41) | TSHRSMN1; SMN2TDP1HSD17B10ALDH1A1 | |
| SCHEMBL11520195 | 0.69 | ALDH1A1 (0.35) | TDP1HSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171446-A | Indazole compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1979-10-16 | — | — | US | disclosed |