SCHEMBL11520376

SCHEMBL11520376

CCc1cccc(CC)c1OO

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.54
GABRB2 P47870 4/20 0.54
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
NLRP3 Q96P20 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
DAO P14920 3/20 0.36
CLCN2 P51788 1/20 0.35
DDO Q99489 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9474531 0.87 GABRA1 (0.46) GABRA1GABRB2ADRA2AADRA2BADRA2C
SCHEMBL11361204 0.79 GABRA1 (0.52) GABRA1GABRB2ADRA2AADRA2BADRA2C
SCHEMBL8408142 0.77 GABRA1 (0.50) GABRA1GABRB2ADRA2AADRA2BADRA2C
SCHEMBL31629366 0.76 GABRA1 (0.50) GABRA1GABRB2ADRA2AADRA2BADRA2C
SCHEMBL11584465 0.75 LTA4H (0.47) GABRA1GABRB2MAPTNPSR1
SCHEMBL27852515 0.75 GABRA1 (0.48) GABRA1GABRB2TP53MAPT
SCHEMBL9637863 0.75 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL61591 0.73 GABRA1 (0.46) GABRA1GABRB2ADRA2AADRA2BADRA2C
SCHEMBL216250 0.73 L3MBTL1 (0.53) GABRA1GABRB2ADRA2AADRA2BADRA2C
SCHEMBL3379051 0.73 SLC2A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4169210-A Oxidation of diethylbenzenes COSDEN TECHNOLOGY, INC. (US) 1979-09-25 US disclosed