Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829971 | 0.83 | DRD2 (0.51) | DRD2DRD3ADRB2DRD1ADRA1D | |
| SCHEMBL6843823 | 0.83 | DRD2 (0.51) | DRD2DRD3ADRB2DRD1ADRA1D | |
| Bromide SCHEMBL7037393 | 0.81 | DRD2 (0.50) | DRD2DRD3ADRB2DRD1ADRA1D | |
| Hydrochloric Acid SCHEMBL6547743 | 0.81 | DRD2 (0.50) | DRD2DRD3ADRB2DRD1ADRA1D | |
| SCHEMBL2956868 | 0.80 | ADRA1D (0.49) | DRD2DRD3ADRB2DRD1ADRA1D | |
| SCHEMBL7781202 | 0.79 | DRD2 (0.44) | DRD2DRD3ADRB2DRD1ADRA1D | |
| Bromide SCHEMBL6008428 | 0.78 | DRD2 (0.50) | DRD2DRD3DRD1ADRA1DADRA1A | |
| SCHEMBL7781192 | 0.77 | DRD2 (0.44) | DRD2DRD3ADRB2DRD1ADRA1D | |
| SCHEMBL7424155 | 0.77 | DRD2 (0.71) | DRD2DRD3DRD1ADRA1DADRA1A | |
| SCHEMBL7424159 | 0.77 | DRD2 (0.71) | DRD2DRD3DRD1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163063-A | MUSCLE RELAXANTS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1979-07-31 | — | — | US | disclosed |
| US-4163063-A | MUSCLE RELAXANTS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1979-07-31 | — | — | US | disclosed |