Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329422 | 0.81 | LMNA (0.52) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL200194 | 0.81 | LMNA (0.52) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL14416057 | 0.79 | ALOX5 (0.51) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL10759383 | 0.79 | ALOX5 (0.56) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL10968029 | 0.78 | ALOX5 (0.50) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL4603985 | 0.78 | ALOX5 (0.46) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL11880683 | 0.76 | ALOX5 (0.53) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL11877876 | 0.76 | ALOX5 (0.45) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL6203157 | 0.76 | CES2 (0.52) | ALOX5CES2CES1LCKFYN | |
| SCHEMBL9814555 | 0.76 | ALOX5 (0.41) | ALOX5CES2CES1LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |