Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenetole SCHEMBL28294450 | 0.86 | NPC1 (0.58) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL8780311 | 0.83 | ALDH1A1 (0.57) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL11044054 | 0.83 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL27666250 | 0.81 | NR4A2 (0.67) | ALDH1A1KMT2AKDM4EMEN1NR1H4 | |
| SCHEMBL5139133 | 0.79 | HPGD (0.68) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL9448786 | 0.78 | ALDH1A1 (0.49) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29505938 | 0.77 | KMT2A (0.75) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL1333545 | 0.77 | KMT2A (0.75) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL307233 | 0.77 | KMT2A (0.75) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29505934 | 0.77 | KMT2A (0.75) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |