Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706965 | 0.81 | ALDH1A1 (0.46) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL13394101 | 0.81 | MAPK1 (0.50) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL279485 | 0.73 | MAPK1 (0.50) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL12523122 | 0.72 | MAPK1 (0.44) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL5157716 | 0.72 | MAPK1 (0.55) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL9853199 | 0.71 | MTNR1A (0.50) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL27703730 | 0.71 | MTNR1A (0.50) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL12267542 | 0.71 | KDM4E (0.48) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL6941443 | 0.71 | MAPK1 (0.43) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL29066999 | 0.71 | MTNR1A (0.36) | MAPK1KDM4EHIF1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170641-A | 1-N-(ω-aminoalkanesulfonyl) derivative of aminoglycosidic antibiotic and process for preparation thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1979-10-09 | — | — | US | disclosed |