Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520972 | 0.84 | RAB9A (0.45) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11522099 | 0.80 | SORT1 (0.41) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11523266 | 0.77 | RAB9A (0.45) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11523524 | 0.76 | NPC1 (0.37) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11524059 | 0.75 | TRPV1 (0.42) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11523410 | 0.74 | CHEK1 (0.54) | — | |
| SCHEMBL11521655 | 0.73 | RAB9A (0.39) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11521485 | 0.73 | MAPT (0.42) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3665409 | 0.73 | MAPT (0.38) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11522579 | 0.73 | MEN1 (0.41) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |