Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665409 | 0.89 | MAPT (0.38) | TRPV1RAB9AMEN1POLBKMT2A | |
| SCHEMBL11522579 | 0.89 | MEN1 (0.41) | TRPV1RAB9AMEN1POLBKMT2A | |
| SCHEMBL11375265 | 0.88 | RAB9A (0.51) | TRPV1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11381909 | 0.83 | ALDH1A1 (0.44) | TRPV1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7628324 | 0.82 | PCTP (0.42) | RAB9APOLBKMT2ANPC1TP53 | |
| SCHEMBL11522099 | 0.80 | SORT1 (0.41) | TRPV1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11525837 | 0.80 | CNR1 (0.42) | TRPV1RAB9AMEN1POLBKMT2A | |
| SCHEMBL11526310 | 0.79 | DHODH (0.43) | RAB9AMEN1POLBKMT2ANPC1 | |
| SCHEMBL11522591 | 0.79 | MAPT (0.39) | RAB9AKMT2APTGFRMAPT | |
| SCHEMBL11523714 | 0.79 | RAB9A (0.43) | RAB9AMEN1POLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | claimed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |