Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671546 | 0.91 | KCNH2 (0.51) | ABCG2KCNH2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11522447 | 0.84 | L3MBTL1 (0.52) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4950622 | 0.82 | NR1H3 (0.53) | L3MBTL1 | |
| SCHEMBL28373072 | 0.81 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL16796535 | 0.81 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL18119917 | 0.81 | CRHBP (0.42) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11521588 | 0.81 | L3MBTL1 (0.42) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11524514 | 0.80 | KCNH2 (0.55) | ABCG2KCNH2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11523856 | 0.79 | NOX1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL19212464 | 0.78 | CA12 (0.47) | KCNH2ALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137328-A | CONGESTIVE HEART FAILURE | PFIZER INC. (US) | 1979-01-30 | — | — | US | disclosed |