SCHEMBL11522989

SCHEMBL11522989

CCOC(=O)N(N)C(=O)N(N)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
ALDH1A1 P00352 5/20 0.43
LMNA P02545 3/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
TRPA1 O75762 1/20 0.37
CYP1A2 P05177 2/20 0.37
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 1/20 0.33
MAOA P21397 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1203240 0.90 ALOX15 (0.50) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL9563960 0.83 ALDH1A1 (0.46) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL9133400 0.83 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL10879392 0.81 ALOX15 (0.42) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL9679886 0.79
SCHEMBL10568938 0.78 ALOX15 (0.39) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL3289896 0.77
SCHEMBL3333830 0.77
SCHEMBL7664573 0.77
SCHEMBL15734005 0.76 NFKB1 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4169954-A 3,3-CARBONYLBIS(CARBAZATES) AS BLOWING AGENTS UNIROYAL, INC. (US) 1979-10-02 US disclosed
US-4105601-A 3,3'-Carbonylbis(carbazates) as blowing agents UNIROYAL, INC. (US) 1978-08-08 US disclosed