Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11658812 | 0.83 | CYP3A4 (0.36) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL7098338 | 0.83 | TP53 (0.39) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1833205 | 0.82 | CYP3A4 (0.38) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1547849 | 0.72 | CYP3A4 (0.56) | CYP2C19SMN1; SMN2HIF1AHPGDHSD17B10 | |
| SCHEMBL10592132 | 0.67 | HSD17B10 (0.59) | CYP2C19SMN1; SMN2HIF1AHPGDHSD17B10 | |
| SCHEMBL9419974 | 0.66 | CYP3A4 (0.43) | HPGDHSD17B10CYP3A4TSHRCRHBP | |
| SCHEMBL10493668 | 0.65 | CYP3A4 (0.35) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL7926904 | 0.64 | SMN1; SMN2 (0.41) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL1764669 | 0.64 | TSHR (0.38) | TP53CYP2C9CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL25978067 | 0.63 | CYP3A4 (0.50) | CYP2C19SMN1; SMN2HIF1AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141912-A | Process for the preparation of polyhalobenzylic disulfooxonium compounds | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-02-27 | — | — | US | disclosed |
| US-4075238-A | Polyhalobenzylic disulfooxonium compounds | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |