SCHEMBL1833205

SCHEMBL1833205

Cc1c(Cl)c(Cl)cc(C(Cl)(Cl)Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11523387 0.82 TP53 (0.35) CYP3A4TSHRMAPK1TP53CYP2C9
SCHEMBL1764669 0.81 TSHR (0.38) CYP3A4TSHRMAPK1TDP1TP53
SCHEMBL10493668 0.77 CYP3A4 (0.35) CYP3A4TSHRMAPK1TDP1TP53
SCHEMBL6417699 0.77 CYP3A4 (0.53) CYP3A4TSHRMAPK1TDP1ALDH1A1
SCHEMBL1547849 0.76 CYP3A4 (0.56) CYP3A4TSHRMAPK1CYP2C19SMN1; SMN2
SCHEMBL11601275 0.73 TSHR (0.44) CYP3A4TSHRMAPK1TDP1ALDH1A1
SCHEMBL8846801 0.71 TSHR (0.43) CYP3A4TSHRMAPK1TDP1ALDH1A1
SCHEMBL10493736 0.71 TSHR (0.43) CYP3A4TSHRMAPK1TDP1ALDH1A1
SCHEMBL8916390 0.70 TSHR (0.41) CYP3A4TSHRMAPK1TDP1TP53
SCHEMBL30855347 0.70 TSHR (0.41) CYP3A4TSHRMAPK1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0132868-A1 Alpha-halogenated aromatic compounds as photoinitiators STAUFFER CHEMICAL COMPANY (US) 1985-02-13 EP claimed
JP-53121733-A None JP disclosed
WO-2024253093-A1 FLUOROSILICONE COMPOUND ダイキン工業株式会社 2024-12-12 WO disclosed
US-20240279396-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE SOLVAY SA (BE) 2024-08-22 US disclosed
US-12065594-B2 Roll and method for producing roll LINTEC CORPORATION (JP) 2024-08-20 US disclosed
EP-4352045-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE SYENSQO SA (BE) 2024-04-17 EP disclosed
WO-2022258332-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE SOLVAY SA (BE) 2022-12-15 WO disclosed
US-11220091-B2 Roll and method for producing roll LINTEC CORPORATION (JP) 2022-01-11 US disclosed
CN-110603300-B Roller and method for manufacturing roller 琳得科株式会社 2021-10-15 CN disclosed
CN-110325609-B Roller and method for manufacturing roller 琳得科株式会社 2021-08-17 CN disclosed
EP-0563033-A1 PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE. CHEVRON RES & TECH (US) 1993-10-06 EP disclosed
WO-1992007820-A1 PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-05-14 WO disclosed
US-4966988-A CHLORINATION FOLLOWED BY FLUORINATION OF M-XYLENE TO FORM 3-TRIFLUOROMETHYL-BENZYL CHLORIDE; CYANATION CHEVRON RESEARCH COMPANY (US) 1990-10-30 US disclosed
US-4165337-A HALOACYLATION OF HEXACHLOROXYLENES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-08-21 US disclosed
JP-S53121733-A PREPARATION OF MIXTURE OF TERE AND ISO-PHTHALIC ACID CHLORIDES SHIN ETSU CHEM CO LTD 1978-10-24 JP disclosed
US-4091017-A FRIEDEL-CRAFTS CATALYSTS, HYDROLYSIS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-05-23 US disclosed
US-4029560-A CHLORINATION OF XYLENE, ULTRAVIOLET RADIATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-06-14 US disclosed
US-4029592-A ANHYDRIDED, HALOGENATED HYDROCARBON, TARRY BY-PRODUCT SUPPRESSANTS STANDARD OIL COMPANY (INDIANA) (US) 1977-06-14 US disclosed
US-3966832-A Continuous process for preparing derivatives of benzene with fluorinated side chains from the corresponding chlorine compounds HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3960900-A POLYBUTENE, MALEIC ANHYDRIDE STANDARD OIL COMPANY (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279396-A1 CYCLIC OLIGO(ARYLENE ETHER)S, PROCESSES FOR THEIR PREPARATION AND THEIR USE PDXK, HCK, DEK CYP3A4 199/4885TSHR 3110/4885MAPK1 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.