Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301677 | 0.84 | GSK3A (0.41) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL11520374 | 0.82 | GSK3A (0.40) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL9301450 | 0.78 | APEX1 (0.58) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL9203370 | 0.78 | APEX1 (0.58) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL9203374 | 0.78 | APEX1 (0.58) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL10681074 | 0.75 | ALDH1A1 (0.43) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL11621290 | 0.75 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL563088 | 0.74 | GSK3A (0.41) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL563087 | 0.74 | GSK3A (0.41) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE | |
| SCHEMBL6949518 | 0.74 | GSK3A (0.41) | GSK3AGSK3BALDH1A1SMN1; SMN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173569-A | Preparation of pyrrolidine and pyrrolidin-2-one derivatives | I.S.F. SPA (IT) | 1979-11-06 | — | — | US | disclosed |