Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523848 | 0.82 | ACHE (0.48) | CACNA1CHTR2BCHRM2CHRM1ADRA2C | |
| SCHEMBL11524725 | 0.79 | CYP24A1 (0.57) | HTR2BDRD2HTR2AHTR2CHTR1A | |
| SCHEMBL11522306 | 0.77 | SIGMAR1 (0.68) | ALDH1A1HTR2BDRD2DRD3HTR1A | |
| Fumaric Acid SCHEMBL11523466 | 0.73 | MEN1 (0.47) | MEN1KMT2AALDH1A1L3MBTL1CACNA1B | |
| Fumaric Acid SCHEMBL11523475 | 0.73 | MEN1 (0.47) | MEN1KMT2AALDH1A1L3MBTL1CACNA1B | |
| SCHEMBL11461926 | 0.73 | HTR1A (0.49) | MEN1KMT2AALDH1A1HTR2BOPRM1 | |
| SCHEMBL11471462 | 0.71 | SIGMAR1 (0.49) | HTR2BDRD2CNR1DRD3HTR1A | |
| SCHEMBL11523471 | 0.71 | MEN1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1CACNA1B | |
| SCHEMBL6502613 | 0.70 | CYP19A1 (0.55) | LMNAHTR2CHTR1ASIGMAR1 | |
| SCHEMBL10494953 | 0.70 | MEN1 (0.63) | MEN1KMT2AALDH1A1L3MBTL1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148897-A | VASODILATOR, CEREBRAL BLOOD FLOW INCREASING | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-10 | — | — | US | disclosed |