Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.68 |
| ▸ | MC4R | P32245 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461926 | 0.84 | HTR1A (0.49) | SIGMAR1HTR1AMC4RACHEALDH1A1 | |
| SCHEMBL11524725 | 0.84 | CYP24A1 (0.57) | SIGMAR1HTR1AMC4RHTR2BDRD2 | |
| SCHEMBL11471462 | 0.84 | SIGMAR1 (0.49) | SIGMAR1HTR1AMC4RACHEMETAP1 | |
| SCHEMBL11523848 | 0.82 | ACHE (0.48) | SIGMAR1HTR1AMC4RACHEHTR2B | |
| SCHEMBL11463426 | 0.81 | POLB (0.48) | SIGMAR1HTR1AMC4RACHEALDH1A1 | |
| SCHEMBL30423421 | 0.80 | METAP1 (0.74) | SIGMAR1HTR1AMC4RACHEMETAP1 | |
| Hydrochloric Acid SCHEMBL29583950 | 0.79 | METAP1 (0.74) | SIGMAR1HTR1AMC4RACHEMETAP1 | |
| SCHEMBL6492064 | 0.79 | SIGMAR1 (0.70) | SIGMAR1HTR1AMC4RACHEMETAP1 | |
| SCHEMBL27646285 | 0.78 | SIGMAR1 (0.68) | SIGMAR1HTR1AMC4RACHEMETAP1 | |
| SCHEMBL11524409 | 0.77 | MEN1 (0.50) | SIGMAR1HTR1AMC4RALDH1A1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148897-A | VASODILATOR, CEREBRAL BLOOD FLOW INCREASING | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-10 | — | — | US | disclosed |