SCHEMBL11525019

SCHEMBL11525019

O=C(Cl)c1ccc(-c2nc(Cl)c(Cl)o2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 3/20 0.41
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPT P10636 3/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 4/20 0.38
LMNA P02545 2/20 0.38
MAP4K4 O95819 1/20 0.38
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TTR P02766 1/20 0.37
ALB P02768 1/20 0.37
MAOA P21397 1/20 0.37
CNR1 P21554 1/20 0.37
DRD1 P21728 1/20 0.37
OPRD1 P41143 1/20 0.37
PDE4D Q08499 1/20 0.37
PDE3A Q14432 1/20 0.37
TARBP2 Q15633 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11524905 0.81 HDAC6 (0.39) IKBKBNPC1RAB9AMAPTALDH1A1
SCHEMBL11523476 0.80 NPC1 (0.45) IKBKBNPC1RAB9AALDH1A1KDM4E
SCHEMBL11527293 0.76 KDM4E (0.49) IKBKBNPC1RAB9AMAPTALDH1A1
SCHEMBL11329502 0.74 ESR1 (0.57) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL11333471 0.73 NPC1 (0.68) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL28551660 0.73 HDAC6 (0.60) NPC1RAB9AMAPTSMN1; SMN2HDAC6
SCHEMBL11384195 0.73 LMNA (0.65) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL11527491 0.71 NPC1 (0.74) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL11528718 0.71 NR4A2 (0.53) NPC1RAB9AALDH1A1KDM4ELMNA
SCHEMBL727046 0.71 ALDH1A1 (0.52) NPC1RAB9AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed