SCHEMBL727046

SCHEMBL727046

O=C(Cl)c1ccc(-c2ccc(C(=O)Cl)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
RXRA P19793 2/20 0.44
RXRB P28702 2/20 0.44
PDPK1 O15530 1/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
BCL2L1 Q07817 1/20 0.44
BAD Q92934 1/20 0.44
HSD17B1 P14061 1/20 0.44
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
PTPN1 P18031 2/20 0.39
GSK3B P49841 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10670934 1.00 ALDH1A1 (0.52) ALDH1A1RXRARXRBPDPK1MAPT
Water SCHEMBL9342313 0.97 ALDH1A1 (0.50) ALDH1A1RXRARXRBPDPK1MAPT
SCHEMBL20587670 0.90 ALDH1A1 (0.59) ALDH1A1MAPTLMNATP53TSHR
SCHEMBL68148 0.90 ALDH1A1 (0.59) ALDH1A1MAPTLMNATP53TSHR
SCHEMBL23630426 0.89 TSHR (0.60) RXRARXRBBCL2L1BADTP53
SCHEMBL2902010 0.89 CES2 (0.56) ALDH1A1RXRARXRBMAPTLMNA
SCHEMBL14416 0.89 SMN1; SMN2 (0.60) ALDH1A1MAPTSMN1; SMN2RAB9AMEN1
Biphenyl SCHEMBL28809192 0.89 SMN1; SMN2 (0.60) ALDH1A1MAPTSMN1; SMN2RAB9AMEN1
SCHEMBL10348291 0.89 TSHR (0.60) RXRARXRBBCL2L1BADTP53
SCHEMBL8723556 0.89 SMN1; SMN2 (0.60) ALDH1A1MAPTSMN1; SMN2RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332075-A1 POLYAMIDE MICROCAPSULES FIRMENICH & CIE (CH) 2025-10-30 US claimed
US-20250312763-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2025-10-09 US claimed
EP-4564066-A1 OPTICAL FILM AND DISPLAY DEVICE COMPRISING SAME Kolon Industries, Inc. (KR) 2025-06-04 EP claimed
US-20250154318-A1 PHTHALIMIDINE- CONTAINING CARDO BISPHENOLS BEARING PENDANT FURYL GROUP AND POLYMERS THEREFROM COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2025-05-15 US claimed
CN-119971800-A High-stability anti-pollution efficient composite reverse osmosis membrane and preparation method thereof 中国矿业大学(北京) 2025-05-13 CN claimed
US-20250130495-A1 POLYBENZOXAZOL PRECURSOR OR POLYIMIDE PRECURSOR OR THE COPOLYMER THEREOF, AND POSITIVE PHOTOSENSITIVE RESIN COMPOSITION THEREFROM DUK SAN NEOLUX CO., LTD. (KR) 2025-04-24 US claimed
US-20250109251-A1 OPTICAL FILM AND METHOD OF PREPARING SAME KOLON INDUSTRIES, INC. (KR) 2025-04-03 US claimed
US-12258306-B2 Diamine, polymer and film produced using the same SK INNOVATION CO., LTD. (KR) 2025-03-25 US claimed
EP-4522325-A1 POLYAMIDE MICROCAPSULES Firmenich SA (CH) 2025-03-19 EP claimed
EP-4522324-A1 POLYAMIDE MICROCAPSULES Firmenich SA (CH) 2025-03-19 EP claimed
EP-0119271-A4 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. STANFORD RES INST INT (US) 1985-07-01 EP claimed
EP-0062005-B1 PROCESS FOR THE MANUFACTURE OF STYRENE AND/OR STILBENE DERIVATIVES CIBA-GEIGY AG (CH) 1985-06-26 EP claimed
EP-0119271-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. STANFORD RES INST INT (US) 1984-09-26 EP claimed
EP-0119192-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS SRI INTERNATIONAL (US) 1984-09-26 EP claimed
WO-1984001160-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO claimed
WO-1984001162-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO claimed
EP-0041043-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE CIBA-GEIGY AG (CH) 1983-11-09 EP claimed
EP-0091778-A2 Improvement in or relating to aromatic polyamide film TEIJIN LIMITED (JP) 1983-10-19 EP claimed
US-4335055-A Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US claimed
US-4169932-A METHOD OF PRODUCING POLY-P-PHENYLENETEREPHTHALAMIDE OR ITS COPOLYMERS INGERSOLL EQUIPMENT CO., INC., 1979-10-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12258306-B2 Diamine, polymer and film produced using the same PUF60, DDT, PARG ALDH1A1 1793/4885RXRA 4039/4885RXRB 4390/4885
US-20250332075-A1 POLYAMIDE MICROCAPSULES PSAP, POLI, PGA5 ALDH1A1 3371/4885RXRA 787/4885RXRB 1493/4885
US-20250312763-A1 POLYAMIDE MICROCAPSULES PSAP, PPHLN1, PARG ALDH1A1 3681/4885RXRA 1217/4885RXRB 1724/4885
US-20250154318-A1 PHTHALIMIDINE- CONTAINING CARDO BISPHENOLS BEARING PENDANT FURYL GROUP AND POLYMERS THEREFROM PCBP1, PBRM1, DPYD ALDH1A1 287/4885RXRA 830/4885RXRB 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.