Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 11/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.64 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 3/20 | 0.57 |
| ▸ | CCKAR | P32238 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236543 | 1.00 | OPRD1 (0.64) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL11525133 | 0.91 | CTSS (0.64) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL11525136 | 0.91 | CTSS (0.64) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL11523721 | 0.91 | CTSS (0.64) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL11684956 | 0.88 | REN (0.60) | CTSSCTSKCTSLCTSB | |
| SCHEMBL11681799 | 0.88 | REN (0.57) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL9819589 | 0.88 | CTSS (0.59) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL8580174 | 0.87 | REN (0.60) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL4018237 | 0.87 | CTSS (0.66) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL11683746 | 0.87 | CTSS (0.66) | OPRD1OPRM1OPRK1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877891-B2 | Method of producing a novel opioid peptide | LIPKOWSKI ANDREJ (PL) | 2014-11-04 | — | — | US | disclosed |
| EP-2384334-B1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEV OF RESARCH SP Z O O (PL) | 2013-02-27 | — | — | EP | disclosed |
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | LIPKOWSKI ANDREJ (PL) | 2012-01-05 | — | — | US | disclosed |
| EP-2384334-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | Action For Development Of Resarch SP.Z.O.O. (PL) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010077154-A1 | A METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | ACTION FOR DEVELOPMENT OF RESARCH SP.Z.O.O. (PL) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004180-A1 | METHOD OF PRODUCING A NOVEL OPIOID PEPTIDE | OPRL1, OPRK1, OGFR | OPRD1 5/4885OPRM1 4/4885OPRK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.