Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527635 | 0.82 | LMNA (0.56) | CHRM2CHRM1CYP3A4LMNACYP1A2 | |
| SCHEMBL11525943 | 0.80 | KDM4E (0.54) | CHRM2CHRM1CYP3A4LMNACYP1A2 | |
| SCHEMBL11528961 | 0.80 | MEN1 (0.55) | CYP3A4CYP1A2CYP2D6TSHRCHRM3 | |
| Hydrochloric Acid SCHEMBL11532127 | 0.79 | MEN1 (0.54) | CYP3A4CYP1A2CYP2D6TSHRCHRM3 | |
| Drofenine SCHEMBL25124 | 0.78 | CHRM2 (1.00) | CHRM2CHRM1CYP3A4LMNACYP1A2 | |
| SCHEMBL11529632 | 0.77 | LMNA (0.50) | CHRM2CHRM1CYP3A4LMNACYP1A2 | |
| Drofenine SCHEMBL446912 | 0.77 | CYP3A4 (1.00) | CHRM2CHRM1CYP3A4LMNACYP1A2 | |
| SCHEMBL11530140 | 0.77 | KDM4E (0.46) | CHRM1CYP3A4LMNACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11528321 | 0.76 | ALDH1A1 (0.51) | CHRM2CHRM1CYP3A4LMNACYP1A2 | |
| Drofenine SCHEMBL1649803 | 0.76 | CHRM2 (0.95) | CHRM2CHRM1CYP3A4LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |