Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527640 | 0.93 | LMNA (0.57) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11525943 | 0.88 | KDM4E (0.54) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11529632 | 0.85 | LMNA (0.50) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11530140 | 0.85 | KDM4E (0.46) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11528321 | 0.84 | ALDH1A1 (0.51) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11567781 | 0.84 | ALDH1A1 (0.46) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11525189 | 0.82 | CHRM2 (0.64) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11530310 | 0.81 | KDM4E (0.48) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11524308 | 0.81 | KDM4E (0.46) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL11530069 | 0.81 | PPARA (0.48) | LMNACYP1A2CYP2D6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |