Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113840 | 0.90 | ADORA3 (0.33) | SMN1; SMN2TP53ADORA3RAB9ALMNA | |
| SCHEMBL115259 | 0.90 | PDE5A (0.33) | SMN1; SMN2TP53ADORA3ALDH1A1HSD17B10 | |
| SCHEMBL115155 | 0.89 | KDM4E (0.35) | SMN1; SMN2TP53RAB9ANPC1GAA | |
| SCHEMBL115300 | 0.86 | ADORA3 (0.34) | SMN1; SMN2TP53ADORA3RAB9ALMNA | |
| SCHEMBL113857 | 0.86 | ALDH1A1 (0.38) | SMN1; SMN2TP53RAB9ANPC1GAA | |
| SCHEMBL115325 | 0.85 | HEXA (0.36) | SMN1; SMN2TP53ADORA3KDM5ARAB9A | |
| SCHEMBL113811 | 0.84 | CASR (0.35) | SMN1; SMN2TP53RAB9ANPC1GAA | |
| SCHEMBL115332 | 0.83 | TLR8 (0.35) | SMN1; SMN2ADORA3RAB9AKDM4EALDH1A1 | |
| SCHEMBL115979 | 0.82 | ADORA3 (0.32) | SMN1; SMN2TP53ADORA3RAB9AMAPK1 | |
| SCHEMBL113824 | 0.82 | ADORA3 (0.32) | SMN1; SMN2TP53ADORA3RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | SMN1; SMN2 4450/4885TP53 4438/4885ADORA3 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.