Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966483 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL2597017 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL4283433 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8429080 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL5829754 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8726527 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8987158 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL4113305 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL2855754 | 0.98 | — | — | |
| SCHEMBL305297 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111944140-B | Polymeric prodrug micelle with reduction responsiveness and preparation method and application thereof | 南开大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-111944140-A | Polymeric prodrug micelle with reduction responsiveness and preparation method and application thereof | 南开大学 | 2020-11-17 | — | — | CN | disclosed |
| US-4135047-A | PREPARATION OF THIOETHERS USING A BENZOPINACOL INITIATOR | W. R. GRACE & CO. (US) | 1979-01-16 | — | — | US | disclosed |