Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966483 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL2597017 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL4283433 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL11525673 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8429080 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL5829754 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8726527 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8987158 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL2855754 | 0.98 | — | — | |
| SCHEMBL305297 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071714-B | Process for producing vinyl chloride-based polymer | 株式会社LG化学 | 2021-03-09 | — | — | CN | claimed |
| US-10766976-B2 | Method of preparing vinyl chloride-based polymer | LG CHEM, LTD. (KR) | 2020-09-08 | — | — | US | claimed |
| EP-3404048-B1 | METHOD FOR PREPARING VINYL CHLORIDE BASED POLYMER | LG CHEMICAL LTD (KR) | 2020-08-26 | — | — | EP | claimed |
| EP-2956487-B1 | USE OF METHYL MERCAPTO-ESTERS AS CHAIN TRANSFER AGENTS | ARKEMA FRANCE (FR) | 2019-04-24 | — | — | EP | claimed |
| US-20190048110-A1 | METHOD OF PREPARING VINYL CHLORIDE-BASED POLYMER | LG CHEM, LTD. (KR) | 2019-02-14 | — | — | US | claimed |
| EP-3404048-A1 | METHOD FOR PREPARING VINYL CHLORIDE BASED POLYMER | LG Chem, Ltd. (KR) | 2018-11-21 | — | — | EP | claimed |
| US-9126919-B2 | Use of mercapto-methyl esters as chain transfer agents | ARKEMA FRANCE (FR) | 2015-09-08 | — | — | US | claimed |
| US-20140235807-A1 | Use of Mercapto-Methyl Esters as Chain Transfer Agents | ARKEMA FRANCE (FR) | 2014-08-21 | — | — | US | claimed |
| CN-109071714-B | Process for producing vinyl chloride-based polymer | 株式会社LG化学 | 2021-03-09 | — | — | CN | disclosed |
| US-10766976-B2 | Method of preparing vinyl chloride-based polymer | LG CHEM, LTD. (KR) | 2020-09-08 | — | — | US | disclosed |
| EP-3404048-B1 | METHOD FOR PREPARING VINYL CHLORIDE BASED POLYMER | LG CHEMICAL LTD (KR) | 2020-08-26 | — | — | EP | disclosed |
| US-20190048110-A1 | METHOD OF PREPARING VINYL CHLORIDE-BASED POLYMER | LG CHEM, LTD. (KR) | 2019-02-14 | — | — | US | disclosed |
| EP-3404048-A1 | METHOD FOR PREPARING VINYL CHLORIDE BASED POLYMER | LG Chem, Ltd. (KR) | 2018-11-21 | — | — | EP | disclosed |
| US-20170008840-A1 | SULFUR-CONTAINING PHENOL DERIVATIVES | ARKEMA FRANCE (FR) | 2017-01-12 | — | — | US | disclosed |
| US-8076299-B2 | Method for producing peptide thioester | RIKEN (JP) | 2011-12-13 | — | — | US | disclosed |
| US-8076299-B2 | Method for producing peptide thioester | RIKEN (JP) | 2011-12-13 | — | — | US | disclosed |
| US-8076299-B2 | Method for producing peptide thioester | RIKEN (JP) | 2011-12-13 | — | — | US | disclosed |
| US-20090240034-A1 | METHOD FOR PRODUCING PEPTIDE THIOESTER | RIKEN (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090240034-A1 | METHOD FOR PRODUCING PEPTIDE THIOESTER | RIKEN (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090240034-A1 | METHOD FOR PRODUCING PEPTIDE THIOESTER | RIKEN (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008840-A1 | SULFUR-CONTAINING PHENOL DERIVATIVES | HSF1, TYR, SQOR | TSHR 3907/4885LMNA 4819/4885ALDH1A1 524/4885 |
| US-20140235807-A1 | Use of Mercapto-Methyl Esters as Chain Transfer Agents | MGMT, MPST, BHMT2 | TSHR 4448/4885LMNA 4695/4885ALDH1A1 229/4885 |
| US-20090240034-A1 | METHOD FOR PRODUCING PEPTIDE THIOESTER | PTMS, PPT1, NGLY1 | TSHR 1448/4885LMNA 4397/4885ALDH1A1 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.