SCHEMBL5829754

SCHEMBL5829754

COC(=O)CCCCCS

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.64
LMNA P02545 2/20 0.55
ALDH1A1 P00352 1/20 0.55
HSD17B10 Q99714 1/20 0.50
FOLH1 Q04609 1/20 0.48
KMT2A Q03164 2/20 0.46
RECQL P46063 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
EPHX2 P34913 3/20 0.42
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
POLA1 P09884 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18966483 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL2597017 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL4283433 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL11525673 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL8429080 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL8726527 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL8987158 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL4113305 1.00 TSHR (0.64) TSHRLMNAALDH1A1HSD17B10FOLH1
SCHEMBL2855754 0.98
SCHEMBL305297 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101492819-B Method for solid supporting ionic liquid on copper heat exchanger surface INST ENG THERMOPHYSICS CAS 2011-01-19 CN claimed
CN-101492819-A Method for solid supporting ionic liquid on copper heat exchanger surface INST ENG THERMOPHYSICS CAS (CN) 2009-07-29 CN claimed
US-4616046-A CONTAINING METALLIC HEAT STABILIZER AND CARBOXY MERCAPTAN COMPOUND ATO CHIMIE (FR) 1986-10-07 US claimed
US-20240417420-A1 POLAR CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS GLYCOMIMETICS, INC. (US) 2024-12-19 US disclosed
WO-2023060021-A1 POLAR CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS MAGNANI JOHN L (US) 2023-04-13 WO disclosed
CN-101492819-B Method for solid supporting ionic liquid on copper heat exchanger surface INST ENG THERMOPHYSICS CAS 2011-01-19 CN disclosed
CN-101492819-A Method for solid supporting ionic liquid on copper heat exchanger surface INST ENG THERMOPHYSICS CAS (CN) 2009-07-29 CN disclosed
US-7153995-B2 Ethyl 3-mercaptobutyrate as a flavoring or fragrance agent and methods for preparing and using same BUSH, BOAKE ALLEN INC. (US) 2006-12-26 US disclosed
US-20060165608-A1 ETHYL 3-MERCAPTOBUTYRATE AS A FLAVORING OR FRAGRANCE AGENT AND METHODS FOR PREPARING AND USING SAME DEWIS MARK L 2006-07-27 US disclosed
US-7074453-B2 Ethyl 3-mercaptobutyrate as a flavoring or fragrance agent and methods for preparing and using same BUSH, BOAKE ALLEN, INC. (US) 2006-07-11 US disclosed
US-6878366-B2 Ethyl 3-mercaptobutyrate as a perfuming agent and methods for preparing and using same BUSH, BOAKE ALLEN, INC. (US) 2005-04-12 US disclosed
US-4696946-A Topical Treatment of hyperproliferative skin diseases SCHERING CORPORATION (US) 1987-09-29 US disclosed
EP-0169033-A2 Inhibitors of slow reacting substance of anaphylaxis SCHERING CORPORATION (US) 1986-01-22 EP disclosed
EP-0051284-B1 NOVEL THIAPROSTAGLANDIN E1 DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS TEIJIN LIMITED (JP) 1985-01-09 EP disclosed
US-4466980-A Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof TEIJIN LIMITED (JP) 1984-08-21 US disclosed
EP-0051284-A1 Novel thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceuticals containing these compounds TEIJIN LIMITED (JP) 1982-05-12 EP disclosed
US-4229588-A FROM A MERCAPTOALKYL ESTER CONTACTED WITH A HALOGEN PHILLIPS PETROLEUM COMPANY (US) 1980-10-21 US disclosed
US-4180672-A 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom TEIJIN LIMITED (JP) 1979-12-25 US disclosed
US-4175201-A Chemical synthesis UNIVERSITY OF CHICAGO (US) 1979-11-20 US disclosed
US-4018820-A Chemical synthesis THE UNIVERSITY OF CHICAGO (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165608-A1 ETHYL 3-MERCAPTOBUTYRATE AS A FLAVORING OR FRAGRANCE AGENT AND METHODS FOR PREPARING AND USING SAME CTH, CBS, MPST TSHR 3740/4885LMNA 4615/4885ALDH1A1 881/4885
US-20240417420-A1 POLAR CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS SIGLEC9, SIGLEC7, ASGR1 TSHR 2469/4885LMNA 2540/4885ALDH1A1 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.