Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966483 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL4283433 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL11525673 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8429080 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL5829754 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8726527 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL8987158 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL4113305 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1HSD17B10FOLH1 | |
| SCHEMBL2855754 | 0.98 | — | — | |
| SCHEMBL305297 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010629-B2 | Compositions and methods for in vivo imaging | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-03 | — | — | US | disclosed |
| US-10010629-B2 | Compositions and methods for in vivo imaging | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180073017-A1 | METHODS FOR SELECTING ENZYMES HAVING ENHANCED ACTIVITY | NOVOZYMES A/S (DK) | 2018-03-15 | — | — | US | disclosed |
| US-20150343094-A1 | COMPOSITIONS AND METHODS FOR IN VIVO IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-12-03 | — | — | US | disclosed |
| US-20150343094-A1 | COMPOSITIONS AND METHODS FOR IN VIVO IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-12-03 | — | — | US | disclosed |
| US-8231969-B2 | Asymmetrically functionalized nanoparticles | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-07-31 | — | — | US | disclosed |
| WO-2011146390-A2 | COMPOSITIONS AND METHODS FOR IN VIVO IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20090256116-A1 | Asymmetrically Functionalized NanoParticles | UNIVERSITY OF UTAH | 2009-10-15 | — | — | US | disclosed |
| EP-0589867-B1 | SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS | PHARMACIA BIOSENSOR AB (SE) | 1996-04-10 | — | — | EP | disclosed |
| US-5436161-A | Matrix coating for sensing surfaces capable of selective biomolecular interactions, to be used in biosensor systems | PHARMACIA BIOSENSOR AB (SE) | 1995-07-25 | — | — | US | disclosed |
| EP-0589867-A1 | SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS. | PHARMACIA BIOSENSOR AB (SE) | 1994-04-06 | — | — | EP | disclosed |
| US-5242828-A | SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS | PHARMACIA BIOSENSOR AB (SE) | 1993-09-07 | — | — | US | disclosed |
| WO-1990005303-A1 | SENSING SURFACES CAPABLE OF SELECTIVE BIOMOLECULAR INTERACTIONS, TO BE USED IN BIOSENSOR SYSTEMS | PHARMACIA AB (SE) | 1990-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150343094-A1 | COMPOSITIONS AND METHODS FOR IN VIVO IMAGING | PLIN3, SGMS1, SGMS2 | TSHR 3625/4885LMNA 682/4885ALDH1A1 3206/4885 |
| US-10010629-B2 | Compositions and methods for in vivo imaging | PLIN3, SGMS1, SGMS2 | TSHR 3625/4885LMNA 682/4885ALDH1A1 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.