Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522548 | 0.89 | AKR1C3 (0.53) | MAPTKDM4EALOX15MAPK1HSD17B10 | |
| SCHEMBL6931398 | 0.88 | HMGB1 (0.49) | GABRA1GABRB2MAPTKDM4EALOX15 | |
| SCHEMBL16949829 | 0.87 | GABRA1 (0.67) | GABRA1GABRB2KDM4EHSD17B10CLCN2 | |
| SCHEMBL28121439 | 0.86 | MAPT (0.58) | GABRA1GABRB2MAPTKDM4EALOX15 | |
| SCHEMBL27639750 | 0.85 | HMGB1 (0.46) | MAPTKDM4EALOX15MAPK1HSD17B10 | |
| SCHEMBL29881091 | 0.85 | AKR1C3 (0.57) | MAPTAKR1C3GAACLCN2ELANE | |
| SCHEMBL723171 | 0.85 | AKR1C3 (0.57) | MAPTAKR1C3GAACLCN2ELANE | |
| SCHEMBL10518375 | 0.84 | L3MBTL1 (0.50) | MAPTKDM4EALOX15MAPK1HSD17B10 | |
| SCHEMBL18928220 | 0.84 | KMT2A (0.65) | GABRA1GABRB2KDM4EALOX15HSD17B10 | |
| SCHEMBL9625731 | 0.84 | AKR1C3 (0.52) | MAPTAKR1C3GAACLCN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017145024-A1 | UV-ABSORBING VINYLIC MONOMERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-08-31 | — | — | WO | disclosed |
| US-4141995-A | Ketone derivatives | LILLY INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | disclosed |