Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639750 | 0.91 | HMGB1 (0.46) | HMGB1MAPTKDM4EALOX15MAPK1 | |
| SCHEMBL11525711 | 0.88 | GABRA1 (0.55) | HMGB1MAPTKDM4EALOX15MAPK1 | |
| SCHEMBL7028825 | 0.88 | HMGB1 (0.51) | HMGB1IAPPPRKCICYP3A4CYP2C9 | |
| SCHEMBL28823845 | 0.88 | BID (0.54) | MAPTKDM4EALOX15HSD17B10PPARG | |
| SCHEMBL7252078 | 0.86 | AKR1C3 (0.52) | MAPTAKR1C3GAAPPARGPPARA | |
| SCHEMBL8522548 | 0.84 | AKR1C3 (0.53) | HMGB1MAPTKDM4EALOX15MAPK1 | |
| SCHEMBL9626492 | 0.84 | AKR1C3 (0.46) | MAPTAKR1C3GAAPPARGPPARA | |
| SCHEMBL7598180 | 0.84 | HMGB1 (0.49) | HMGB1MAPTKDM4EALOX15MAPK1 | |
| SCHEMBL3070365 | 0.83 | CA2 (0.42) | HMGB1MAPTKDM4EALOX15MAPK1 | |
| SCHEMBL9859 | 0.83 | HMGB1 (0.69) | HMGB1KDM4EHSD17B10IAPPMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600224-B1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2026-05-06 | — | — | EP | claimed |
| US-12214067-B2 | Oil-in-water emulsion sunscreen composition | ISP INVESTMENTS INC. (US) | 2025-02-04 | — | — | US | claimed |
| US-20220387290-A1 | SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2022-12-08 | — | — | US | claimed |
| US-20220125701-A1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2022-04-28 | — | — | US | claimed |
| EP-3946642-A1 | SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF | ISP Investments LLC (US) | 2022-02-09 | — | — | EP | claimed |
| EP-3600224-B1 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF | ISP INVESTMENTS LLC (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2026044006-A1 | MODIFIED STARCH COMPOUNDS AND USES THEREOF | ISP INVESTMENTS LLC (US) | 2026-02-26 | — | — | WO | disclosed |
| EP-4683973-A2 | DISPERSANT COMPOSITIONS COMPRISING HYDROPHOBIC AND HYDROPHILIC MODIFIED MALEATED NATURAL OILS, AND APPLICATIONS THEREOF | ISP Investments LLC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-12497478-B2 | High molecular weight block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophilic monomers, compositions, and applications thereof | ISP INVESTMENTS LLC (US) | 2025-12-16 | — | — | US | disclosed |
| US-20250360066-A1 | COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE | ROKA FURADADA S L (ES) | 2025-11-27 | — | — | US | disclosed |
| US-12472207-B2 | Anti-inflammatory compositions and methods | RR MEDSCIENCES PTY LTD. (AU) | 2025-11-18 | — | — | US | disclosed |
| EP-4604907-A1 | A METHOD OF PROVIDING HIGH SPF TO A TOPICAL SURFACE OF A BODY | Unilever IP Holdings B.V. (NL) | 2025-08-27 | — | — | EP | disclosed |
| CN-104784057-A | Sunscreen compositions | WYETH LLC | 2015-07-22 | — | — | CN | disclosed |
| CN-102573766-B | Sunscreen compositions | WYETH LLC | 2015-05-27 | — | — | CN | disclosed |
| CN-103596542-A | Clear wet sprays and gels | ISP INVESTMENTS INC | 2014-02-19 | — | — | CN | disclosed |
| CN-102573766-A | Sunscreen compositions | WYETH LLC | 2012-07-11 | — | — | CN | disclosed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12497478-B2 | High molecular weight block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophilic monomers, compositions, and applications thereof | MRPL9, PRMT9, MRPL19 | HMGB1 45/4885MAPT 3882/4885KDM4E 2470/4885 |
| US-20250360066-A1 | COMPOSITION COMPRISING A PHOTOCHEMICAL ULTRAVIOLET ABSORBER PRECURSOR AND A COMPOUND FOR INCREASING THEIR PHOTOCHEMICAL CONVERSION RATE | TYR, PAH, ERCC4 | HMGB1 3900/4885MAPT 387/4885KDM4E 2920/4885 |
| US-12472207-B2 | Anti-inflammatory compositions and methods | SOD3, MPO, SOD1 | HMGB1 90/4885MAPT 3741/4885KDM4E 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.