Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012161 | 0.91 | NPSR1 (0.34) | ADRB1KMT2ANPSR1HSP90AA1CCR6 | |
| SCHEMBL1012948 | 0.89 | ADRB1 (0.44) | CHRM2CHRM4ADRB1CHRM1CHRM3 | |
| SCHEMBL11527050 | 0.87 | MAPT (0.40) | CHRM2CHRM4ADRB1CHRM1CHRM3 | |
| SCHEMBL11528889 | 0.82 | MAPT (0.39) | ADRB1KMT2ANPSR1TSHRMAPT | |
| SCHEMBL11525941 | 0.78 | HTR3E (0.44) | NPSR1TSHRMAPT | |
| SCHEMBL1012216 | 0.75 | MAPT (0.49) | ADRB1KMT2ANPSR1HSP90AA1NOTUM | |
| SCHEMBL11527859 | 0.75 | MAPT (0.42) | KMT2ANPSR1MAPTHTTSMN1; SMN2 | |
| SCHEMBL11529526 | 0.74 | HTR2A (0.44) | ADRB1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL1011864 | 0.73 | MAPT (0.47) | ADRB1KMT2ANPSR1HSP90AA1MAPT | |
| SCHEMBL1010858 | 0.72 | NPSR1 (0.33) | NPSR1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161528-A | INSECTICIDES; MITICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1979-07-17 | — | — | US | disclosed |