Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012161 | 0.90 | NPSR1 (0.34) | MAPTALDH1A1TSHRPOLBNPSR1 | |
| SCHEMBL11530804 | 0.87 | MAPT (0.46) | MAPTALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL1012009 | 0.86 | MAPT (0.44) | MAPTALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL1012216 | 0.83 | MAPT (0.49) | MAPTTSHRNPSR1ADRB1SMN1; SMN2 | |
| SCHEMBL11525866 | 0.82 | CHRM2 (0.37) | MAPTTSHRNPSR1ADRB1SMN1; SMN2 | |
| SCHEMBL1011864 | 0.79 | MAPT (0.47) | MAPTALDH1A1NPSR1ADRB1SMN1; SMN2 | |
| SCHEMBL1010053 | 0.78 | DRD4 (0.40) | MAPTALDH1A1NPSR1SMN1; SMN2KMT2A | |
| SCHEMBL11525941 | 0.77 | HTR3E (0.44) | MAPTTSHRPOLBNPSR1L3MBTL1 | |
| SCHEMBL11527050 | 0.76 | MAPT (0.40) | MAPTALDH1A1POLBNPSR1ADRB1 | |
| SCHEMBL11529526 | 0.76 | HTR2A (0.44) | MAPTALDH1A1KDM4EPOLBADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161528-A | INSECTICIDES; MITICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1979-07-17 | — | — | US | disclosed |