Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012216 | 0.92 | MAPT (0.49) | MAPTTSHRNPSR1GFERL3MBTL1 | |
| SCHEMBL395284 | 0.91 | HTR2A (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11529526 | 0.90 | HTR2A (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11524094 | 0.85 | HTR2A (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11525866 | 0.78 | CHRM2 (0.37) | MAPTTSHRNPSR1 | |
| SCHEMBL11528889 | 0.77 | MAPT (0.39) | MAPTTSHRNPSR1POLBL3MBTL1 | |
| SCHEMBL11527050 | 0.76 | MAPT (0.40) | MAPTNPSR1TP53POLBL3MBTL1 | |
| SCHEMBL1012161 | 0.76 | NPSR1 (0.34) | MAPTTSHRNPSR1POLB | |
| SCHEMBL1012948 | 0.73 | ADRB1 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11530804 | 0.73 | MAPT (0.46) | MAPTTSHRNPSR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161528-A | INSECTICIDES; MITICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1979-07-17 | — | — | US | disclosed |