Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010081 | 0.85 | ADRB1 (0.43) | GAAHPGDTSHRMAPTLMNA | |
| SCHEMBL1011864 | 0.75 | MAPT (0.47) | L3MBTL1GAAHPGDMAPTTDP1 | |
| SCHEMBL1012105 | 0.75 | HRH3 (0.40) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1012216 | 0.73 | MAPT (0.49) | L3MBTL1TSHRMAPTLMNANPSR1 | |
| SCHEMBL1012161 | 0.72 | NPSR1 (0.34) | TSHRMAPTLMNANPSR1ADRB1 | |
| SCHEMBL11530804 | 0.70 | MAPT (0.46) | L3MBTL1TSHRMAPTTDP1LMNA | |
| SCHEMBL11526360 | 0.70 | KAT2B (0.41) | GAAHPGDMAPTALDH1A1 | |
| SCHEMBL11527050 | 0.70 | MAPT (0.40) | L3MBTL1GAAHPGDMAPTTDP1 | |
| SCHEMBL1010938 | 0.68 | LTA4H (0.33) | — | |
| SCHEMBL1012040 | 0.68 | KDM4E (0.40) | L3MBTL1GAAHPGDTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161528-A | INSECTICIDES; MITICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1979-07-17 | — | — | US | disclosed |