Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011864 | 0.93 | MAPT (0.47) | MAPTALDH1A1NPSR1TDP1LMNA | |
| SCHEMBL1012009 | 0.89 | MAPT (0.44) | MAPTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL11528889 | 0.87 | MAPT (0.39) | MAPTALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL11527859 | 0.86 | MAPT (0.42) | MAPTALDH1A1NPSR1TDP1LMNA | |
| SCHEMBL11529526 | 0.85 | HTR2A (0.44) | MAPTALDH1A1TDP1LMNAL3MBTL1 | |
| SCHEMBL1010053 | 0.84 | DRD4 (0.40) | MAPTALDH1A1NPSR1LMNAL3MBTL1 | |
| SCHEMBL1010359 | 0.82 | SIGMAR1 (0.44) | MAPTALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL11524986 | 0.82 | ALDH1A1 (0.40) | MAPTALDH1A1NPSR1TDP1LMNA | |
| SCHEMBL11530511 | 0.82 | ACHE (0.47) | MAPTALDH1A1NPSR1TDP1LMNA | |
| SCHEMBL11527050 | 0.82 | MAPT (0.40) | MAPTALDH1A1NPSR1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161528-A | INSECTICIDES; MITICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1979-07-17 | — | — | US | disclosed |