Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.77 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | TP53 | P04637 | 6/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | HTT | P42858 | 6/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | CNR2 | P34972 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496676 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL5582025 | 0.86 | ALDH1A1 (1.00) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL22819342 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL19275978 | 0.84 | KDM4E (0.77) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL5009162 | 0.84 | KDM4E (0.77) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL10061946 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL10061943 | 0.83 | KDM4E (0.70) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL3431636 | 0.83 | ALDH1A1 (0.79) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL10443668 | 0.82 | ALDH1A1 (0.92) | KDM4EALDH1A1LMNANPSR1TSHR | |
| SCHEMBL28141462 | 0.82 | KDM4E (0.75) | KDM4EALDH1A1LMNANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022265-A1 | MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM | BERG-SCHULTZ KATJA (CH) | 2012-01-26 | — | — | US | disclosed |
| US-20100256082-A1 | Metallo-hydrolase inhibitors using metal binding moietes in combination with targeting moieties | VIAMET PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20080089852-A1 | copolymeric (meth)acrylic esters or (meth)acrylic amides containing a chromophore having uv absorption properties selected from aminobenzoates, camphors, cinnamates, benzophenones, benzalmalonic esters, esters of 2-(4-ethoxy anilinomethylene)propandioic, imidazoles, acrylates, phenyl-benzimidazoles | DSM IP ASSETS B.V. (NL) | 2008-04-17 | — | — | US | disclosed |
| US-20070190325-A1 | Microcapsules with uv filter activity and process for producing them | DSM IP ASSETS B.V. (NL) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256082-A1 | Metallo-hydrolase inhibitors using metal binding moietes in combination with targeting moieties | MMEL1, MPI, METAP1 | KDM4E 1756/4885ALDH1A1 322/4885LMNA 4580/4885 |
| US-20120022265-A1 | MICROCAPSULES WITH UV FILTER ACTIVITY AND PROCESS FOR PRODUCING THEM | UACA, UROD, UMPS | KDM4E 3121/4885ALDH1A1 3001/4885LMNA 472/4885 |
| US-20070190325-A1 | Microcapsules with uv filter activity and process for producing them | UACA, UROD, UMPS | KDM4E 3121/4885ALDH1A1 3001/4885LMNA 472/4885 |
| US-20080089852-A1 | copolymeric (meth)acrylic esters or (meth)acrylic amides containing a chromophore having uv absorption properties selected from aminobenzoates, camphors, cinnamates, benzophenones, benzalmalonic esters, esters of 2-(4-ethoxy anilinomethylene)propandioic, imidazoles, acrylates, phenyl-benzimidazoles | PAH, ACMSD, AAAS | KDM4E 537/4885ALDH1A1 65/4885LMNA 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.