Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526297 | 0.71 | KMO (0.37) | NOTUMALDH1A1KCNH2 | |
| SCHEMBL12835399 | 0.67 | ALDH1A1 (0.65) | LMNAMAPTCYP2C19MAPK1ALDH1A1 | |
| SCHEMBL5490306 | 0.66 | CHRM2 (0.45) | NOTUMKCNH2MEN1KMT2A | |
| SCHEMBL16505883 | 0.65 | KMO (0.68) | LMNAMAPTNOTUM | |
| SCHEMBL1942998 | 0.65 | POLQ (0.41) | LMNANOTUMALDH1A1HTTPOLB | |
| SCHEMBL9009142 | 0.64 | NOTUM (0.41) | NOTUMKCNH2MEN1KMT2A | |
| SCHEMBL27712572 | 0.64 | NOTUM (0.41) | NOTUMKCNH2MEN1KMT2A | |
| SCHEMBL17060479 | 0.64 | HTR3E (0.47) | LMNAGRM4 | |
| SCHEMBL6607454 | 0.63 | KMO (0.39) | LMNAMAPTNOTUMMAPK1ALDH1A1 | |
| SCHEMBL1039397 | 0.62 | AR (0.45) | NOTUMALDH1A1KCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162329-A | Combating fungi with dicarboxylic acid mono-arylhydrazides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |