SCHEMBL11526

SCHEMBL11526

FC(F)(F)c1ccccc1I

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
IDO1 P14902 2/20 0.40
CA2 P00918 1/20 0.40
TSHR P16473 1/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.39
HSD11B1 P28845 1/20 0.38
NFKB1 P19838 1/20 0.38
KIF11 P52732 1/20 0.38
HTR2C P28335 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29673099 1.00 ALDH1A1 (0.43) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL3677273 0.83 ALDH1A1 (0.33) ALDH1A1TDP1POLBL3MBTL1IDO1
Trifluoromethanesulfonic Acid SCHEMBL2228760 0.83 MEN1 (0.40) ALDH1A1CA2TSHRLMNAGAA
SCHEMBL27733344 0.80 ALDH1A1 (0.45) ALDH1A1TDP1POLBTSHRMEN1
SCHEMBL3672313 0.79 ALDH1A1 (0.31) ALDH1A1TDP1POLBL3MBTL1TSHR
SCHEMBL28028231 0.79 KIF11 (0.31) ALDH1A1TDP1POLBL3MBTL1TSHR
SCHEMBL8499174 0.79 KDM4E (0.37) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL63469 0.78 ALDH1A1 (0.52) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL29441997 0.78 ALDH1A1 (0.52) ALDH1A1TDP1POLBL3MBTL1IDO1
SCHEMBL12326344 0.77 MPL (0.40) ALDH1A1TDP1POLBL3MBTL1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 628 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119583-A Method for producing fluorine-containing aromatic compound 大金工业株式会社 2024-05-31 CN claimed
CN-117886706-A Monoamine monomer containing trifluoromethyl and alkynyl, application of monoamine monomer, photosensitive polyimide film and preparation method of photosensitive polyimide film 安徽国风新材料股份有限公司 2024-04-16 CN claimed
CN-114957092-A Organic luminescent material, preparation method and application 南京邮电大学 2022-08-30 CN claimed
CN-111484503-B Mikanolide derivative and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2022-05-27 CN claimed
CN-114394891-A Compound prepared by catalyzing chalcone with monovalent iodine reagent, and preparation method and application thereof 化学与精细化工广东省实验室 2022-04-26 CN claimed
CN-111484503-A Mikanolide derivative and preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2020-08-04 CN claimed
CN-106588788-B The method of one pot of two-step method synthesis 1,2,3- triazole compound 河南师范大学 2019-07-16 CN claimed
CN-109772310-A A kind of preparation and its application of mesoporous silicon supported palladium nanocluster catalyst 鲁东大学 2019-05-21 CN claimed
CN-106588693-B A kind of synthetic method of aryl azide compound 河南师范大学 2019-01-18 CN claimed
CN-109206384-A Room temperature phosphorimetry molecule based on phenothiazine derivative and its preparation method and application 武汉大学 2019-01-15 CN claimed
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP claimed
CN-100400529-C Fluorine-containing aromatic organic tetracarboxylic dianhydride and preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2008-07-09 CN claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
CN-1247512-C Process for preparing trifluoromethyl acetophenone compound UNIV ZHEJIANG POLYTECHNIC (CN) 2006-03-29 CN claimed
CN-1605587-A Fluorine-containing aromatic organic tetracarboxylic dianhydride and preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2005-04-13 CN claimed
CN-1587246-A Process for preparing trifluoromethyl acetophenone compound UNIV ZHEJIANG POLYTECHNIC (CN) 2005-03-02 CN claimed
EP-0354078-B1 DERIVATIVES OF BENZOCYCLOHEPTENE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME ADIR ET COMPAGNIE (FR) 1993-03-10 EP claimed
EP-0354078-A2 Derivatives of benzocycloheptene, method for their preparation and pharmaceutical compositions containing same ADIR ET COMPAGNIE (FR) 1990-02-07 EP claimed
EP-0070198-B1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME Hitachi, Ltd. (JP) 1985-06-19 EP claimed
EP-0070198-A1 Radiation-sensitive composition and pattern-formation method using the same Hitachi, Ltd. (JP) 1983-01-19 EP claimed