Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597167 | 0.87 | ALDH1A1 (0.39) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL29673099 | 0.79 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL11526 | 0.79 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL30364632 | 0.78 | MPL (0.40) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL6992159 | 0.78 | HSD11B1 (0.40) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL12326344 | 0.78 | MPL (0.40) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL12327631 | 0.78 | HSD11B1 (0.38) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB | |
| SCHEMBL29163752 | 0.77 | NOTUM (0.37) | POLBGAA | |
| SCHEMBL2264731 | 0.77 | — | — | |
| SCHEMBL25434956 | 0.76 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2HSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354078-B1 | DERIVATIVES OF BENZOCYCLOHEPTENE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1993-03-10 | — | — | EP | claimed |
| EP-0354078-A2 | Derivatives of benzocycloheptene, method for their preparation and pharmaceutical compositions containing same | ADIR ET COMPAGNIE (FR) | 1990-02-07 | — | — | EP | claimed |
| EP-0956312-A1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR Corporation (JP) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998033836-A1 | PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL | JSR CORPORATION (JP) | 1998-08-06 | — | — | WO | disclosed |
| EP-0354078-B1 | DERIVATIVES OF BENZOCYCLOHEPTENE, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1993-03-10 | — | — | EP | disclosed |
| EP-0354078-A2 | Derivatives of benzocycloheptene, method for their preparation and pharmaceutical compositions containing same | ADIR ET COMPAGNIE (FR) | 1990-02-07 | — | — | EP | disclosed |
| EP-0113625-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLATED BENZENIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1985-07-10 | — | — | EP | disclosed |
| EP-0113625-A1 | Process for the preparation of trifluoromethylated benzenic compounds | RHONE-POULENC CHIMIE (FR) | 1984-07-18 | — | — | EP | disclosed |