Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305534 | 0.94 | ZDHHC20 (0.46) | CYP1A2L3MBTL1KMT2AHPGDZDHHC20 | |
| SCHEMBL11347354 | 0.86 | ZDHHC20 (0.42) | CYP1A2L3MBTL1ZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL7508667 | 0.79 | CA12 (0.46) | L3MBTL1KMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL22400003 | 0.79 | L3MBTL1 (0.42) | L3MBTL1KMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL11527916 | 0.79 | CYP1A2 (0.47) | CYP1A2L3MBTL1KMT2AHPGDALDH1A1 | |
| SCHEMBL134357 | 0.79 | ALDH1A1 (0.50) | L3MBTL1KMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL17956782 | 0.79 | GRIN2D (0.39) | KMT2AZDHHC20ZDHHC2ALDH1A1GRIN2D | |
| SCHEMBL28428750 | 0.79 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2ALDH1A1MAPTHTT | |
| SCHEMBL7514061 | 0.76 | CA12 (0.55) | L3MBTL1ZDHHC20ZDHHC2ALDH1A1EPHX1 | |
| SCHEMBL11336109 | 0.76 | ALDH1A1 (0.42) | L3MBTL1ZDHHC20ZDHHC2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10767112-B2 | Methods of producing metal sulfides, metal selenides, and metal sulfides/selenides having controlled architectures using kinetic control | THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-08 | — | — | US | disclosed |
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |