Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524978 | 0.86 | HCAR3 (0.50) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL10998326 | 0.77 | HCAR3 (0.50) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL14690957 | 0.73 | L3MBTL1 (0.49) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL29392877 | 0.73 | L3MBTL1 (0.49) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL8373915 | 0.73 | L3MBTL1 (0.49) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL21821 | 0.73 | L3MBTL1 (0.49) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL8057686 | 0.72 | L3MBTL1 (0.48) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL20723668 | 0.72 | L3MBTL1 (0.48) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28262613 | 0.72 | ALDH1A1 (0.38) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 | |
| Pendimethalin SCHEMBL27926297 | 0.72 | L3MBTL1 (0.48) | HCAR3MAPTSMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119669-A | PREEMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1978-10-10 | — | — | US | claimed |
| US-4136117-A | PREPARATION OF 2,6-DINITROANILINES | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |
| US-4119669-A | PREEMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1978-10-10 | — | — | US | disclosed |