Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526154 | 0.86 | HCAR3 (0.48) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL17268395 | 0.75 | HCAR3 (0.46) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL1133304 | 0.74 | ALDH1A1 (0.58) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL11215144 | 0.74 | ALDH1A1 (0.67) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL10249259 | 0.73 | HCAR3 (0.68) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL11523263 | 0.72 | ALDH1A1 (0.60) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL3192684 | 0.70 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TDP1TSHRSMN1; SMN2 | |
| SCHEMBL23924910 | 0.70 | KMT2A (0.50) | ALDH1A1CYP1A2TDP1MAPTSMN1; SMN2 | |
| SCHEMBL13598830 | 0.70 | HCAR3 (0.61) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL8810869 | 0.70 | HCAR3 (0.68) | HCAR3ALDH1A1CYP3A4L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136117-A | PREPARATION OF 2,6-DINITROANILINES | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |
| US-4119669-A | PREEMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1978-10-10 | — | — | US | disclosed |