Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | TYK2 | P29597 | 4/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372025 | 0.89 | CCNA2 (0.42) | TSHRSMN1; SMN2GHSRRAB9APPIA | |
| SCHEMBL11520972 | 0.84 | RAB9A (0.45) | JAK2TYK2JAK1SMN1; SMN2MAPT | |
| SCHEMBL11368780 | 0.81 | NPC1 (0.46) | SMN1; SMN2MAPTRAB9AGAA | |
| SCHEMBL11521949 | 0.81 | ABL1 (0.43) | JAK2TYK2JAK1CDK9JAK3 | |
| SCHEMBL11520974 | 0.79 | TYK2 (0.45) | JAK2TYK2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11523714 | 0.76 | RAB9A (0.43) | JAK2TYK2JAK1SMN1; SMN2MAPT | |
| SCHEMBL11524573 | 0.76 | RAB9A (0.46) | JAK2TYK2JAK1CDK9JAK3 | |
| SCHEMBL11525837 | 0.75 | CNR1 (0.42) | JAK2TYK2JAK1SMN1; SMN2MAPT | |
| SCHEMBL11526201 | 0.75 | TYK2 (0.45) | JAK2TYK2JAK1SMN1; SMN2MAPT | |
| SCHEMBL11523661 | 0.75 | MAPT (0.43) | JAK2TYK2JAK1MAPTGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |