Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121111 | 0.96 | MAPT (0.50) | MAPTALDH1A1LMNAHTTKMT2A | |
| Hydrochloric Acid SCHEMBL933510 | 0.94 | MAPT (0.53) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL24894419 | 0.89 | PYCR1 (0.47) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL11667015 | 0.85 | ALDH1A1 (0.56) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL859872 | 0.83 | ESR1 (0.50) | MAPTALDH1A1LMNAHTTBCHE | |
| SCHEMBL189440 | 0.83 | MAPT (0.60) | MAPTLMNAKMT2AMEN1TAAR1 | |
| Bromide SCHEMBL20912804 | 0.81 | MAPT (0.58) | MAPTKMT2AMEN1TAAR1BCHE | |
| Water SCHEMBL20912805 | 0.81 | MAPT (0.58) | MAPTKMT2AMEN1TAAR1BCHE | |
| SCHEMBL194697 | 0.80 | BCHE (0.42) | MAPTALDH1A1LMNAHTTKMT2A | |
| SCHEMBL12677859 | 0.77 | MAPT (0.70) | MAPTALDH1A1LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139499-A | Thermally reversible amphoteric ion exchange resins of improved demineralization capacity | ICI AUSTRALIA LIMITED (AU) | 1979-02-13 | — | — | US | claimed |
| US-4086299-A | WITH UNSATURATED CARBOXY ACID | ICI AUSTRALIA LIMITED (AU) | 1978-04-25 | — | — | US | claimed |
| US-4086299-A | WITH UNSATURATED CARBOXY ACID | ICI AUSTRALIA LIMITED (AU) | 1978-04-25 | — | — | US | disclosed |