SCHEMBL11526468

SCHEMBL11526468

CCOC(=O)C1=C(C(=O)OC)C2C=CC1C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.47
KDM4E B2RXH2 5/20 0.43
HTT P42858 1/20 0.42
HSD17B10 Q99714 3/20 0.41
LMNA P02545 3/20 0.41
TSHR P16473 3/20 0.41
TP53 P04637 3/20 0.41
HPGD P15428 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP2C9 P11712 3/20 0.41
CYP3A4 P08684 3/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
KMT2A Q03164 2/20 0.41
HIF1A Q16665 2/20 0.41
SLC6A3 Q01959 2/20 0.41
GAA P10253 2/20 0.41
CYP2D6 P10635 1/20 0.41
NFKB1 P19838 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11582658 0.93 LMNA (0.46) KDM4EHTTHSD17B10LMNATSHR
SCHEMBL4192960 0.87 SLC6A3 (0.42) KDM4EHSD17B10LMNATSHRCYP3A4
SCHEMBL13947949 0.79 SLC6A3 (0.38) KDM4ETSHRALDH1A1MEN1KMT2A
SCHEMBL11583334 0.79 SLC6A3 (0.41) HTTHSD17B10LMNATSHRTP53
SCHEMBL11593386 0.79 ESR1 (0.52) KDM4EHSD17B10LMNATSHRTP53
SCHEMBL11529327 0.79 SLC6A3 (0.36) ADORA3HSD17B10TSHRHPGDALDH1A1
SCHEMBL11529785 0.78 ALDH1A1 (0.48) KDM4EHSD17B10LMNATSHRTP53
SCHEMBL18501037 0.77 ALDH1A1 (0.43) KDM4EHSD17B10TSHRALDH1A1GAA
SCHEMBL11525443 0.77 MAPK1 (0.37) HTTTP53ALDH1A1KMT2APDE4D
SCHEMBL11527344 0.76 CNR1 (0.34) ADORA3HSD17B10TSHRALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4132750-A RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES SHOWA DENKO K.K. (JP) 1979-01-02 US disclosed
US-4105608-A HIGH IMPACT COMPOSITION OF RING-OPENING POLYMERIZATION PRODUCT SHOWA DENKO K.K. (JP) 1978-08-08 US disclosed
US-4059561-A AND A HALOGEN COMPOUND SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-11-22 US disclosed
US-4028482-A LOW VISCOSITY POLYALKENAMER SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-06-07 US disclosed
US-4022954-A ADHESIVES, FLOCCULATING AGENTS, ION EXCHANGE RESINS, MOLDING AGENTS SHOWA DENKO KABUSHIKI KAISHA (JA) 1977-05-10 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed