Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 2/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.48 |
| ▸ | PER2 | O15055 | 1/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | PARK7 | Q99497 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529967 | 0.87 | BRD4 (0.55) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL8146689 | 0.84 | BMPR1B (0.47) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL7824808 | 0.84 | MEN1 (0.42) | PER2CRY2BRD4CHRM1GAA | |
| SCHEMBL29577669 | 0.81 | HRH1 (0.47) | CHRM1ALDH1A1PTGDR2CHRM5CHRM3 | |
| SCHEMBL31356492 | 0.81 | BMPR1B (0.46) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL26021803 | 0.81 | BMPR1B (0.48) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL5116351 | 0.81 | ATAD2 (0.57) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL22667347 | 0.81 | BMPR1B (0.51) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL10749668 | 0.81 | BMPR1B (0.48) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29578483 | 0.80 | CHRM1 (0.53) | CHRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160032-A | Oxindoles as sleep-inducers | SANDOZ, INC. (US) | 1979-07-03 | — | — | US | disclosed |