SCHEMBL11529967

SCHEMBL11529967

CCN1C(=O)Cc2cc(F)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.55
PARK7 Q99497 1/20 0.51
GAA P10253 2/20 0.51
ALDH1A1 P00352 1/20 0.51
ATAD2 Q6PL18 1/20 0.49
BMPR1B O00238 2/20 0.46
BMPR1A P36894 2/20 0.46
TGFBR1 P36897 2/20 0.46
ACVRL1 P37023 2/20 0.46
ACVR1 Q04771 2/20 0.46
PER2 O15055 1/20 0.42
CRY2 Q49AN0 1/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.41
MEN1 O00255 1/20 0.40
CASP6 P55212 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526850 0.87 BMPR1B (0.48) BRD4PARK7GAAALDH1A1ATAD2
SCHEMBL11528886 0.87 PARK7 (0.47) BRD4PARK7GAAALDH1A1ATAD2
SCHEMBL9665354 0.83 BRD4 (0.46) BRD4PARK7GAAALDH1A1ATAD2
SCHEMBL399175 0.81 BRD4 (0.56) BRD4GAAALDH1A1ATAD2BMPR1B
SCHEMBL8146689 0.81 BMPR1B (0.47) BRD4GAAALDH1A1BMPR1BBMPR1A
SCHEMBL7824808 0.81 MEN1 (0.42) BRD4GAAALDH1A1PER2CRY2
SCHEMBL11526516 0.80 BRD4 (0.55) BRD4GAAALDH1A1ATAD2BMPR1B
SCHEMBL30661535 0.80 ATAD2 (0.74) BRD4GAAALDH1A1ATAD2BMPR1B
SCHEMBL4105161 0.80 ATAD2 (0.74) BRD4GAAALDH1A1ATAD2BMPR1B
SCHEMBL9665333 0.80 BRD4 (0.55) BRD4GAAALDH1A1ATAD2BMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4160032-A Oxindoles as sleep-inducers SANDOZ, INC. (US) 1979-07-03 US disclosed