Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.67 |
| ▸ | THRA | P10827 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743613 | 0.83 | THRA (0.63) | THRBTHRAKMT2A | |
| SCHEMBL7825230 | 0.83 | THRA (0.63) | THRBTHRAKMT2A | |
| SCHEMBL6741405 | 0.81 | THRB (0.62) | THRBTHRAKMT2AMCHR1 | |
| SCHEMBL27317432 | 0.81 | THRA (0.61) | THRBTHRAKMT2A | |
| SCHEMBL31361829 | 0.80 | THRB (0.59) | THRBTHRAKMT2AMCHR1PAX8 | |
| SCHEMBL7086075 | 0.79 | THRA (0.59) | THRBTHRAKMT2A | |
| SCHEMBL3270801 | 0.78 | THRB (0.58) | THRBTHRAMCHR1 | |
| SCHEMBL15174539 | 0.78 | THRA (0.77) | THRBTHRAKMT2AHAO1 | |
| SCHEMBL9745362 | 0.78 | THRB (0.50) | THRBTHRAMCHR1 | |
| SCHEMBL8388153 | 0.78 | THRA (0.77) | THRBTHRAKMT2AHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174969-A | THIOETHER DEVELOPMENT INHIBITOR COMPOUND | AGFA-GEVAERT, A.G. (DE) | 1979-11-20 | — | — | US | disclosed |