Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.38 |
| ▸ | WEE1 | P30291 | 4/20 | 0.38 |
| ▸ | STK10 | O94804 | 4/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530530 | 0.86 | KDR (0.44) | KDRCHEK1WEE1STK10SLK | |
| SCHEMBL11529207 | 0.84 | GSK3B (0.42) | KDRCHEK1WEE1STK10SLK | |
| SCHEMBL11531116 | 0.73 | CHEK1 (0.35) | CHEK1WEE1STK10SLKGSK3B | |
| SCHEMBL19930436 | 0.67 | CA1 (0.46) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL11717134 | 0.67 | KDM4E (0.43) | KDRSTK10SLKGSK3BCDK4 | |
| SCHEMBL11712851 | 0.64 | KDR (0.41) | KDRGSK3BCDK4CCND1GSK3A | |
| SCHEMBL11717630 | 0.64 | GSK3B (0.38) | KDRSTK10SLKGSK3BCDK4 | |
| SCHEMBL12627519 | 0.64 | ALDH1A1 (0.54) | ABCG2MAOAMEN1KMT2AALDH1A1 | |
| SCHEMBL11712171 | 0.63 | KDM4E (0.64) | KDRGSK3BCDK4CCND1MEN1 | |
| SCHEMBL11448733 | 0.62 | GRK6 (0.46) | CHEK1WEE1GSK3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139532-A | OPTICAL BRIGHTENERS FOR POLYESTERS AND THEIR BLENDS WITH COTTON | BASF AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |