Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | CDK4 | P11802 | 6/20 | 0.39 |
| ▸ | CCND1 | P24385 | 6/20 | 0.39 |
| ▸ | GSK3B | P49841 | 6/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718359 | 0.86 | EGFR (0.41) | KDM4ECYP1A2CYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL11716003 | 0.84 | PTGER4 (0.39) | CYP1A2CDK4CCND1GSK3BCDK5 | |
| SCHEMBL11712851 | 0.84 | KDR (0.41) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL11712229 | 0.84 | MAOA (0.41) | KDM4EALDH1A1KDRCDK4CCND1 | |
| SCHEMBL11717630 | 0.84 | GSK3B (0.38) | ALDH1A1KDRCDK4CCND1GSK3B | |
| SCHEMBL11713383 | 0.83 | GSK3B (0.36) | ALDH1A1KDRCDK4CCND1GSK3B | |
| SCHEMBL11712171 | 0.82 | KDM4E (0.64) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL11530530 | 0.81 | KDR (0.44) | ALDH1A1KDRCDK4CCND1GSK3B | |
| SCHEMBL11711439 | 0.81 | KDM4E (0.39) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL11712853 | 0.81 | PTGER4 (0.37) | KDM4EALDH1A1SMN1; SMN2KDRCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |